Time-adaptive FEM for distributed parameter identification in mathematical model of HIV infection with drug therapy

Paper i proceeding, 2015

We propose a time-adaptive finite element method for the solution of a parameter identification problem for ODE system which describes dynamics of primary HIV infection with drug therapy. We present framework of a posteriori error estimate in the Tikhonov functional and in the Lagrangian. We also formulate the time-mesh refinement recommendation and an adaptive algorithm to find optimal values of the distributed parameter in our identification problem.