An unexpected triethylsilane-triggered rearrangement of thioaurones to thioflavonols under SPPS conditions
Journal article, 2008
Thioaurones are converted to a mixture of thiaindenes and thioflavonols when exposed to reaction conditions employed in SPPS, that is, treatment with trifluoroacetic acid in the presence of triethylsilane.
Chromophores
Silanes
Reduction
Rearrangement
Thioaurone
Hemithioindigo
Peptidomimetics
Author
Miranda Varedian
Uppsala Universitet
Vratislav Langer
Chalmers, Chemical and Biological Engineering, Environmental Inorganic Chemistry
Jonas Bergquist
Uppsala Universitet
Adolf Gogoll
Uppsala Universitet
Tetrahedron Letters
0040-4039 (ISSN)
Vol. 49 42 6033-6035Subject Categories (SSIF 2011)
Organic Chemistry
DOI
10.1016/j.tetlet.2008.07.054