Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease
Journal article, 2017
© 2017 Elsevier Inc. Plasma mannose levels are elevated in subjects with insulin resistance independently of obesity. Here, we found that elevated plasma mannose levels are strong markers of future risk of several chronic diseases including T2D, CVD, and albuminuria, and that it may contribute to their development rather than just being a novel biomarker.
Glucose-Tolerance
Resistance
Insulin Sensitivity
Author
Adil Mardinoglu
Chalmers, Biology and Biological Engineering, Systems and Synthetic Biology
A. Stancakova
Ita-Suomen yliopisto
L. A. Lotta
University of Cambridge
J. Kuusisto
Ita-Suomen yliopisto
Jan Borén
Sahlgrenska Universitetssjukhuset
M. Bluher
Universitat Leipzig
N. J. Wareham
University of Cambridge
E. Ferrannini
Istituto di Fisiologia Clinica del CNR
P. H. Groop
Helsinki University Central Hospital
Baker Heart and Diabetes Institute
Biomedicum Helsinki
M. Laakso
Ita-Suomen yliopisto
C. Langenberg
University of Cambridge
U. Smith
Sahlgrenska Universitetssjukhuset
Cell Metabolism
1550-4131 (ISSN)
Vol. 26 2 281-283Subject Categories (SSIF 2011)
Cell and Molecular Biology
DOI
10.1016/j.cmet.2017.07.006