Observation of Brownian Relaxation of Magnetic Nanoparticles using HTS SQUID
Journal article, 2017
We analyzed the sensitivity of a separationless immunoassay scheme using functionalized magnetic nanoparticles (MNPs) and a sensitive HTS SQUID magnetometer. The signal of a 100 mu L sample at a concentration of 1 mg/mL and field of 7.5 nT was 20 m Phi(0). This makes it possible for the sensitivity to be within the range of 50 ng/mL at the required time of up to 100 s per a point in the frequency spectrum.
Physics
immunoassay
high-temperature superconducting films
magnetic
SQUID
magnetometry
Author
O. V. Snigirev
Lomonosov Moscow State University
, II Soloviev
Lomonosov Moscow State University
Alexei Kalaboukhov
Chalmers, Microtechnology and Nanoscience (MC2), Quantum Device Physics
Maxim Chukharkin Leonidovich
Chalmers, Microtechnology and Nanoscience (MC2), Quantum Device Physics
Moscow University Physics Bulletin (English Translation of Vestnik Moskovskogo Universiteta, Fizika)
0027-1349 (ISSN)
Vol. 72 1 95-100Areas of Advance
Nanoscience and Nanotechnology
Subject Categories (SSIF 2011)
Analytical Chemistry
DOI
10.3103/s0027134917010143