Approaches to study yeast cell aging and death
Journal article, 2014
For millennia, yeast has been exploited to obtain fermentation products, such as foods and beverages. For c. 50years, yeast has been an established model organism for basic and applied research, and more specifically, for c. 15years, this unicellular organism has been applied to dissect molecular mechanisms of cell aging and programmed cell death. In this review, we present an overview of approaches to study cell aging and death in yeast, including lifespan assessments, calorie restriction, cell viability, survival, and death markers.
CHRONOLOGICAL LIFE-SPAN
yeast cell death
SACCHAROMYCES-CEREVISIAE
span
PROTEIN-KINASE
MODEL SYSTEM
oxidative stress
replicative life
MITOCHONDRIAL FISSION
CHROMOSOMAL REARRANGEMENTS
yeast survival
chronological life span
CALORIE RESTRICTION
Saccharomyces cerevisiae
SYSTEMS BIOLOGY
ALPHA-SYNUCLEIN
STATIONARY-PHASE
Author
M. G. Mirisola
Universita degli Studi di Palermo
R. J. Braun
Universitat Bayreuth
Dina Petranovic Nielsen
Chalmers, Chemical and Biological Engineering, Life Sciences
FEMS Yeast Research
1567-1356 (ISSN) 1567-1364 (eISSN)
Vol. 14 1 109-118Subject Categories (SSIF 2011)
Chemical Sciences
DOI
10.1111/1567-1364.12112