High-T-c superconducting quantum interference device recordings of spontaneous brain activity: Towards high-T-c magnetoencephalography

Journal article, 2012

We have performed single-and two-channel high transition temperature (high-T-c) superconducting quantum interference device (SQUID) magnetoencephalography (MEG) recordings of spontaneous brain activity in two healthy human subjects. We demonstrate modulation of two well-known brain rhythms: the occipital alpha rhythm and the mu rhythm found in the motor cortex. We further show that despite higher noise-levels compared to their low-T-c counterparts, high-T-c SQUIDs can be used to detect and record physiologically relevant brain rhythms with comparable signal-to-noise ratios. These results indicate the utility of high-T-c technology in MEG recordings of a broader range of brain activity.