Magnetic resonance analysis of capillary formation reaction front dynamics in alginate gels
Journal article, 2011
The formation of heterogeneous structures in biopolymer gels is of current interest for biomedical applications and is of fundamental interest to understanding the molecular level origins of structures generated from disordered solutions by reactions. The cation-mediated physical gelation of alginate by calcium and copper is analyzed using magnetic resonance measurements of spatially resolved molecular dynamics during gel front propagation. Relaxation time and pulse-field gradient methods are applied to determine the impact of ion front motion on molecular translational dynamics. The formation of capillaries in alginate copper gels is correlated to changes in translational dynamics.
heavy-metal uptake
relaxation
scaffolds
glassy-polymers
magnetic resonance
capillary
imaging mri
NMR
MRI
diffusion
transition
relaxation
dissipative dynamics
alginate
gelation
gelation
microscopy
formation
calcium cations
pulsed-field gradient
Author
J. E. Maneval
Bucknell University
Diana Bernin
Chalmers, Chemical and Biological Engineering, Applied Surface Chemistry
SuMo Biomaterials
H. T. Fabich
Montana State University - Bozeman
J. D. Seymour
Montana State University - Bozeman
S. L. Codd
Montana State University - Bozeman
Magnetic Resonance in Chemistry
0749-1581 (ISSN) 1097-458X (eISSN)
Vol. 49 10 627-640Subject Categories (SSIF 2011)
Chemical Sciences
DOI
10.1002/mrc.2788