Bacterial cellulose-based materials and medical devices: current state and perspectives
Journal article, 2011
Bacterial cellulose (BC) is a unique and promising material for use as implants and scaffolds in tissue engineering. It is composed of a pure cellulose nanofiber mesh spun by bacteria. It is remarkable for its strength and its ability to be engineered structurally and chemically at nano-, micro-, and macroscales. Its high water content and purity make the material biocompatible for multiple medical applications. Its biocompatibility, mechanical strength, chemical and morphologic controllability make it a natural choice for use in the body in biomedical devices with broader application than has yet been utilized. This paper reviews the current state of understanding of bacterial cellulose, known methods for controlling its physical and chemical structure (e.g., porosity, fiber alignment, etc.), biomedical applications for which it is currently being used, or investigated for use, challenges yet to be overcome, and future possibilities for BC.
v24-5
1990
proliferation
biocompatibility
biomimetic synthesis
biomedical applications
Bacterial cellulose
tissue
scaffolds
p253
Microbial cellulose
Biocompatibility
abdominal-wall
Acetobacter xylinum
bone
Biomedical
ntana jd
Nanocellulose
microbial cellulose
agitated culture
Author
N. Petersen
University of Virginia Medical School
Paul Gatenholm
Chalmers, Chemical and Biological Engineering, Polymer Technology
Applied Microbiology and Biotechnology
0175-7598 (ISSN) 1432-0614 (eISSN)
Vol. 91 5 1277-1286Subject Categories (SSIF 2011)
Chemical Sciences
DOI
10.1007/s00253-011-3432-y