Management regimes in science-based innovation: control and uncertainty during early phases of new drug development
Journal article, 2011
The international pharmaceutical industry is facing a challenge in terms of being able to deliver new and innovative drugs at lower cost. During the last 10 years, a range of new scientific procedures and technologies has been introduced into the industry, partially derived from the advancement of genomics research. However, to date, few have resulted in new registered drugs. In addition to the new technologies, various managerial techniques and methods have been introduced with the intention of increasing the transparency of operations. This paper reports on a study of how scientists during the early phases of new drug development conceive of this present management regime emphasising quantitative output. Thinking of new drug development as an intellectual pursuit in order to understand the elementary mechanisms of the biological organisms on the molecular level, scientists call for an understanding and adjustment of the managerial techniques structuring this work, accompanied by ambiguities and uncertainty.
organizational routines
adaptation
identity
knowledge
performance
product-innovation
new drug development
biotechnology
innovation
science-based
management regime
pharmaceutical industry
creativity
networks
mindfulness
Author
Alexander Styhre
Chalmers, Technology Management and Economics
M. Sundgren
AstraZeneca Sweden
Technology Analysis and Strategic Management
0953-7325 (ISSN)
Vol. 23 5 567-581Subject Categories (SSIF 2011)
Production Engineering, Human Work Science and Ergonomics
DOI
10.1080/09537325.2011.565671